Chronic pyelonephritis will trigger uremia?

Chronic pyelonephritis if permanently disabled, repeated attacks, will ultimately lead to chronic renal failure and uremia that; Conversely, scored uremic patients, such as renal secondary infection, uremia aggravating factors. Clinical often to see that happen, once kidney infection under control, often relieve symptoms of uremia, called reversible factors. Uremia and renal infection, treatment is difficult because : ① uremic patients, renal blood flow, antibacterials in renal concentration achieved within the required time-consuming and therefore are prone to bacterial resistance. ② uremic kidney infection with the bacteria, often in the hospital ill and thus more resistant strains. ③ the use of antibacterial drugs contradictions, such as : uremia, in order to avoid systemic poisoning, often reduce the use of antibacterial drugs, But reductions, antibacterials in renal concentration it is not easy to achieve sterilization level, the poor result. ④ uremia, a lot of nephrotoxicity take up the antibacterial drugs or banned, such as : polymyxin, polymyxin, kanamycin, streptavidin, including vancomycin nephrotoxicity strong caution. Tetracycline drugs will add azotemia, Dan furan I acridine in renal failure associated with the use of optic neuritis and other toxic symptoms, Therefore, in uremia be appropriate to use. ⑤ uremic patients with dysfunction drug excretion, if a long course of treatment, esp poisoning. Some people eager to cure, long uninterrupted medication, it will not only fails to achieve its aim, but has also led to drug resistance of bacteria to invade even lead to two kinds of bacteria infection, but treatment to bring even greater difficulties. In recent years, new antibiotics have been commissioned, treatment programs continuously updated. chronic pyelonephritis the clinical cure rate has increased. Domestic several comprehensive report six weeks after the regular antibiotic treatment, will kill the bacteria in urine as much as 31% ~ 42%. Meanwhile, chronic pyelonephritis associated with malformations, obstruction, vesicoureteral reflux surgery success rates were also increased. a group of 147 cases of chronic pyelonephritis cases, there were 49 patients who had more than 13 years, yet entered uremia. In short, chronic pyelonephritis repeated attacks, permanently disabled, and finally to trigger uremia. However, after the regular antibiotic treatment, and promptly correct urinary tract malformations, obstruction and other factors, is the availability of clinical cure. What is worth mentioning is that in chronic renal failure patients, about 20% is from the development of chronic pyelonephritis come, therefore, chronic pyelonephritis should pay close attention. However, apart from the chronic pyelonephritis, urinary tract infection is generally not develop into chronic renal failure. Even pyelonephritis, cystitis repeated attack, if it is not abnormal urinary tract, such as urinary tract obstruction. vesicoureteral reflux exist, develop into chronic renal failure possibility is minimal.