Clinical application of cyclosporine treatment of a glomerul

Glomerular disease treatment, the dose of cyclosporine A should treat renal function may be. Normal renal function of patients, the recommended dose of cyclosporine A-induced adult to 5 mg / kg · d, children 6 mg / kg per day. Kidney dysfunction, the initial dose was not more than two .5mg/kg d. Cyclosporin A treatment in January and the reaction Eventually the case, recommended Compatibility small dose of estrogen. If treatment with cyclosporin A in March failed to respond, it is desirable to stop. As for the maintenance treatment of cyclosporine A long, at present there is no mature experience, However desirability of cyclosporine A to maintain the minimum effective dose. Cyclosporin A reduction to the individual, mainly on the basis of the response to treatment and the tolerance of the body (side-effects is the level of serum creatinine) to adjust. If serum creatinine after treatment increased, reaching base value of 30%, even in the normal range, should also reduce 25% ~ 50% of the dose. Reducing drug, such as an on serum creatinine values have not dropped the base value 30%, it is desirable to stop. If there with cyclosporine A and the hypertension drug is difficult to control, it should stop. While wearing interference of cyclosporine A blood concentration of drug, but also to adjust the dose of cyclosporine A. 