Monday, March 10, 2008
Pneumococcal pneumonia treatment
Sensitive to penicillin strain of pneumonia ball, penicillin G is the drug of first choice. Non-critical patients can be oral penicillin G or V250~500mg. Every six hours a meeting. without the complications of pneumococcal pneumonia recommend penicillin G50~200 agent intravenous injection of 10,000 u So, every 4-6 hours of a meeting. About 25% of pneumococcal resistance to penicillin. In the United States, clinical isolates, Penicillin resistance or high relative rate of 15% -30%, while in other parts of the world, particularly Spain, Japan, Israel, South Africa and Western Europe, resistance rates higher. Many of penicillin-resistant strains of the same to other antibiotics resistance. with a μ g Oxacilline dish applicable in the detection of drug resistant strains. ≤ 19mm inhibition zone of separation were then used to be thinner broth detection. the highly resistant strain Treatment should be based on in vitro susceptibility testing. High-dose penicillin, cefotaxime or ceftriaxone for most resistant strains effective. a new generation quinolones (levofloxacin, sparfloxacin, grepafloxacin and asked facha Star) is penicillin-resistant strains of the regular use of drugs also for the treatment of penicillin-sensitive strains of the drug to be replaced. Vancomycin as the sole activity of a long-lasting drug of all pneumococcal have antibacterial activity, as in most cases accompanied by a high incidence of penicillin resistance in patients with severe drug of choice. Other effective drugs, including cephalosporins, erythromycin and clindamycin. Tetracycline resistant pneumococcal poor reliability of the results, severely ill patients should not be used. Oral medication including erythromycin or lincomycin - 300mg every 6 hours a time. Gastrointestinal drug for cefotaxime including intravenous grams every six hours; Grams of intravenous ceftriaxone, every 12 hours; Cefazolin intravenous injection of 500 mg every 8 hours a time, Intravenous erythromycin ,58, every six hours; Clindamycin 300~600mg or intravenous injection, every 6-8 hours a time. In addition to cefotaxime and ceftriaxone, Most of the third-generation cephalosporins right pneumococcal relative antibacterial activity. If suspected meningitis, the patient should be given to cefotaxime 2g intravenous injection, every 4-6 hours or an intravenous ceftriaxone grams per 12 hours a time, Given 1g vancomycin intravenously every 12 hours 1st ,increase with or without use of rifampin oral imatinib until know susceptibility results. right empyema patients, In addition to antibiotics, treatment should include appropriate drainage. support treatment, including bed rest, added pleural fluid and against the use of analgesic pain. have cyanosis, obviously the lack of oxygen, severe respiratory difficulties,Cycle disorder or delirium patients should reoxygenation. When oxygen to constantly check blood gas ,particularly for chronic lung disease patients. general propositions over the age of 35 patients follow-up X-ray examination. Chest X ray examination may be in a few weeks will be able to see the invasion dissipate, serious condition and has the original bacteremia or chronic lung disease patients in particular. Treatment began six weeks or six weeks still infiltrating, could be indicative of primary bronchial new biological or TB.
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