Polycystic ovarian syndrome

[Treatment] (1) the treatment of infertility patients to high-carbohydrate diet and low-fat food. 1. Ovulation drugs commonly used method ① clomiphene citrate alone, it could hypothalamus, pituitary level of endogenous estrogen receptor competition, the inhibition of estrogen negative feedback, increase GnRH pulse frequency, FSH and LH adjustment proportion. Drug dose systematically, a total of 5, the menstrual cycle in the first five days of the administration beginning, If the first cycle of treatment ineffective, the second cycle of drug dose is increased to 100 mg were on the 5th. Induced ovulation can be as high as 80% ② Clomiphene citrate and dexamethasone, such as clomiphene citrate alone invalid, dexamethasone can 0.5mg/d; ③ GnRH treatment, Large doses GnRHA (200-5000 μ g) subcutaneously once daily for 4 weeks. Then gonadotropin (hMG) to enable follicle development, the treatment of three cycles pregnancy rate may be raised to 77% ④ hMG treatment for clomiphene invalid, usual dose of two daily intramuscular injection needle (each containing needles FSH75u/LH75u) from menstruation 2-3 days administration, B-5-7 days indicates a poor follicle development increased to a daily dose of three or four needles. When the follicles reach 18~20mm hMG5000~10000u available intramuscular ovulation induction. Treatment should be in B - and serum estradiol and other strict custody; ⑤ abroad in recent years introduced pure FSH treatment with clomiphene citrate to void the PCOS patients, initially a daily dose. continuing 8-14 days without reaction, a daily half-added support, the largest dose of 1.5 ~ 3 support. This low dose FSH slow incremental program of pregnancy 16%~35%; ⑥ PCOS patients with elevated PRL, Bromocriptine can be added to improve the luteal function. 2. Surgical treatment of drug therapy may be in the laparoscopic follicular puncture, or laser coagulation, blood estrogen, androgen levels drop. Application has been little ovarian wedge resection prevent bleeding, infection and pelvic adhesions. (2) Multi-hair treatment ① oral contraceptives; ② security spironolactone, androgen inhibitors 50~200mg/d; ③ dexamethasone for the treatment of adrenal androgen excess hyperandrogenism, 0.25 service every night, Hydrocortisone Acetate Hydrocortisone and the pine can be used to treat hirsutism; ④ gonadotropin-releasing hormone agonists (LHRH-A) is a new treatment of hirsutism drug Da 0 μ MP by subcutaneous injection or nasal spray, which lasted for 6 months.