Several reasons for psoriasis summary

?٠with genetic : a parent suffering from psoriasis, their children suffering from psoriasis for the possibility of 30%. If both parents have cancer, their children suffering from psoriasis for the possibility of 50% -60% The incidence of genetic background further environmental factors, the effect of that multi-gene genetic diseases. ?ڠrelated infection : psoriasis patients with the disease before tonsillectomy, the history of pharyngitis. In psoriasis damage Staphylococcus aureus bacteria and staying with a marked increase. In pustular psoriasis lesions accompanied by a more visible inflammation; Callus in purulent skin Staphylococcus not too much, therefore, Steroid use in the treatment of the disease is not clear. In psoriasis skin damage bacteria and the infection increased significantly, especially streptococcal infections, psoriasis often acute exacerbation, anti Streptococcus "0" high proliferation. ?۠recent study shows the incidence of psoriasis immunity with a very important relationship. ?ܠpsoriasis incidence and mental trauma, emotional tension, trauma, surgery, diet, drugs, skin macules. inappropriate topical or oral administration of drugs and drug-related incidence of the disease. Psoriasis pathophysiology of the important change is accelerating the proliferation of epidermal cells, epidermal cells shorten the turnover time, Epidermal normal turnover time is about 26 -28 days, and psoriatic skin replacement for 3-4 days. Thus epidermal cells mature disrupted, resulting in cutaneous histological, biochemical and diagonalization of the chaos and produce white subtype. Tension swift formation of decline and transparent horny reduce particle phenomena. The researchers discovered epidermal cells Central an adenosine monophosphate (cAMP) levels and lower the RP - cyclic monophosphate (CGMP) water Ping increase prompted epidermal cells cultured; In patients with psoriasis and skin blood extracted polyamines significantly higher than normal. Therefore the pathogenesis of psoriasis and polyamines have a certain relationship changes. Polymorphonuclear leukocytes in the pathogenesis of psoriasis play an important role. As polymorphonuclear leukocyte migration of epidermal gathered in the stratum corneum, saying MUNRO-ulcer pathology of psoriasis is one of the performance. Years of research confirmed that psoriasis dander contains more leukocyte chemotactic factor, These chemokines can complement decomposition from the debris, but also from bacteria, denatured protein. In psoriasis damaged epidermal cells increased serine protease, instead of complement activation caused, Neutrophils Set plot and inflammatory, anti-epidermal keratinocytes protein antibodies and epidermal keratinocyte antigen binding, Complement activation can cause skin inflammation, on polymorphonuclear leukocytes in the pathogenesis of psoriasis to a certain extent. Chinese medicine that causes psoriasis main eating Festival, the impassioned internal evils well versed in many aspects, such as, If not diet, namely Anabaena fresh seafood, over tea liquor, too greasy food raw, the result of the spleen operation dysfunctional, the Health wet heat, P <0.05;>