Friday, March 7, 2008
Treatment of hyperthyroidism during pregnancy Put under Tabo
Generally, hyperthyroidism better not healed before pregnancy. If pregnant, should be given to appropriate treatment. Pregnancy usually not add hyperthyroidism during pregnancy and the postpartum should fight for the right of the mother and fetus had no effect on the conditions, so that the resumption of normal thyroid function. Treatment should pay attention to the following points : 1. Since pregnancy 12 ~ 14 weeks, the fetal thyroid iodine Poly function, so taboo with radioactive iodine treatment, the main choice of medical treatment. 2. Drug treatment of antithyroid drug dose should not be too large, thiourea drugs of choice PTU. Because of the drug through the placenta than other drugs for less, and the cycle block T4 to T3 conversion role. The amount should not be too large, the general began 50 -100 mg once daily for three of them, and Symptoms improved to minimize the amount of 25 -50 mg daily service a time, a late pregnancy may stop, to maintain thyroid function in slightly higher than the normal level and avoid excessive treatment. incurred maternal and fetal hypothyroidism or fetal goiter formation. Propranolol can pass through the placenta, and can cause arising from the continued contraction of small placenta and fetal stunting, bradycardia, premature and newborn respiratory depression, it should be careful in using or not. 3. As antithyroid drugs from the milk secretion, and post-need to continue medication, it would not be appropriate breastfeeding. 4. Hyperthyroidism in pregnancy generally suitable for thyroid total resection, as planned surgery, the desirability of the mid-pregnancy (pregnancy 4 ~ 6 months) purposes. 5. Plus thyroid hormones on the prevention of fetal hypothyroidism unhelpful, and interferes with the blood of thyroid hormone monitoring, is not conducive to adjustment PTU dosage, not possible.
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