Thursday, March 6, 2008
What is refractory hypertension, and how treatment?
Most patients with hypertension after anti-hypertension drug treatment, the blood pressure can be controlled at a satisfactory level, and a small number of patients with hypertension despite receiving a higher dose drug treatment, diastolic blood pressure continued to increase, maintained at 15.2 kPa (115mm Hg) and above, known as refractory hypertension. Intractable complex etiology of hypertension, the general from the following areas of investigation reasons. (1) some improper diet in patients with essential hypertension is caused by improper diet. Hypertension is suffering from neglect after the diet, such as arbitrary Hu eat drink, tobacco, liquor, sugar, fat, offal and other animal reject Ji. increased atherosclerosis, affecting vascular flexibility to vasospasm, which blood very difficult, therefore, Antihypertensive effect of serving the poor. (2) improper medication administration of a single, to the neglect of a comprehensive drug treatment, are often hypertension Jiuzhi without lowering the reasons why, Hypertensive patients to the attention of combination. Attention should also be given to adhere to medication, neither can be seen as good withdrawal, it must not result Jiuzhi blood pressure drop and abandon the treatment. refractory patients with hypertension often lifelong medication. (3) ineffective for weight loss obesity-hypertension, obesity often with high blood pressure showed balance in the relationship Such patients with hypertension if we continue to rely antihypertensive medication, rather than lost weight, blood pressure decreased often poor, and so, In addition to these patients antihypertensive treatment, but also to lose weight. (4) poor spirit and high blood pressure are closely related to poor mental state because of emotional instability. sympathetic in a state of tension, the body of catecholamine secretion and vascular contraction. BP Jiuzhi further decline, it is necessary to pay attention to hypertension patients self-conciliation, and maintain a pleasant mood, irritable mood overcome. (5) Movement less than patients with hypertension do not love, energy expenditure is too small to eat sleep, sleep eating, relying solely on the antihypertensive drug treatment, blood pressure often Jiuzhi decline, therefore, patients with hypertension should strengthen education. Sports can not only lower blood pressure, but also eliminating fat weight loss, regulate psychological balance, improved mental state of tension. For refractory hypertension, the blood pressure as long as it can find no reason for the drop, reasonable treatment, Jiuzhi without lowering the blood pressure more can be changed. Refractory hypertension current antihypertensive drugs more choice advocates combination. Generally the preferred calcium antagonists, such as nifedipine, nitrendipine, the characteristics of such drugs is the role of lasting side effects, effective and reliable. Treatment if blood pressure drop unsatisfactory, arteriosclerosis heavier, larger pulse pressure can increase with angiotensin converting enzyme inhibitors, such as captopril or enalapril, combined with softening vascular medicine vitamin C, niacin tablets; If the heart rate faster, Canada should use beta-blockers, such as propranolol, Atenolol or the U.S. metoprolol; If the diastolic blood pressure, pulse pressure in a small, body fat, increase appropriate use should be diuretics, hydrochlorothiazide and triamterene MTX in, but it should be noted potassium to prevent the electrolyte disorder, Meanwhile plus obesity-reducing drug clofibrate, nicotinic acid inositol lipid, and other oryzanol.
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