Bone Tumor

Overview of bone tumors occurred in the skeletal or its subsidiary organizations tumor, to be common. With the body, like other organizations, the exact etiology is unknown; Bone tumors are benign, malignant, the benign bone tumor easy radical, good prognosis, malignant bone tumors developed rapidly, poor prognosis and high mortality. Etiology and Pathogenesis a pathology, bone tumors. (1) benign. 1. Osteoma. 2. Osteoid osteoma and osteoblastoma. (2) malignant. 1. Osteosarcoma. 2. Juxtacortical osteosarcoma. 2, chondroblastic tumors. (1) benign. (2) malignant. 1. Chondrosarcoma. 2. Near cortex chondrosarcoma. 3. Mesenchymal chondrosarcoma. 3, the giant cell tumor of bone. 4, bone marrow tumors. 1. Ewing's sarcoma. 2. Reticulated bone sarcoma cells. 3. Bone lymphosarcoma. 4. Myeloma. 5, vascular tumors. 6, and other connective tissue tumors. (1) benign. 1. Fibroblasts fibroma. 2. Lipoma. (2) malignant. 7, other tumors. 8, undifferentiated tumors. 9, tumor-like lesions. Clinical manifestations of benign bone tumors grow slowly, the pain is mild or no pain. Cancer was invasive growth, rapid development, early pain and there was sexual heavier. Late anemia and for cachexia, can occur multiple metastatic lesions, with the most common lung metastasis. (1) Pain : bone tumors is a major symptom. (2) mass : often manifested in the limb or trunk of the uplift anomaly. (3) age : the crowd because of cancer deaths are the peak age of two. A 15 to 20 years old, another 30 to 75 years. (4) site features : some bone tumors are more specific the lesion. 1.X ray inspection to clear bone tumor nature, type, scope and determine policy can provide valuable information, bone tumors is an important method of examination. 2. In the pelvis, spine and other parts of the tumor, the ordinary X-ray can not be properly displayed, CT scanning, ultrasound, MRI, ECT, and other new imaging technologies can help determine the location of the tumor and scope. 3. Isotope bone scan in ordinary X-ray has not yet positive changes show that the primary, secondary bone tumors exist. Suspicious should be selective for the 99 technetium bone scan. 4. Histological examination : a final diagnosis of bone tumors depend on the completion of histologic examination, usually access to regular biopsy specimens. Treatment of a benign tumor. More partial resection or without bone graft mainly, if completely removed, generally do not relapse to the good after. 2 malignant tumor. 1. Surgical resection is the treatment of the principal means. Amputations, joint disconnection is the most commonly used method. However, chemotherapy advances, in recent years some scholars began for tumor resection of the femur or total excision, artificial prosthesis. Reservations limbs "partial resection extensive reconstruction," complemented by measures such as chemotherapy, is a desirable approach. 2. Chemical treatment of systemic chemotherapy pm, local chemotherapy, a commonly used drug doxorubicin and high-dose methotrexate. However, the role of selective drugs is not strong, and tumor cells in the split cycle is not synchronized, and this affects chemotherapy. 3. Local intra-arterial chemotherapy, including continuing chemotherapy and regional perfusion and regional perfusion with better effect. 4. Immunotherapy : interferon its limited resources, it is not widely used. 5. Radiotherapy for the treatment of bone tumors only as an adjuvant therapy.