Monday, March 10, 2008

Burn sepsis

Under the group outlined a statistical wounded 5,506 cases 501 cases of sepsis occur, the incidence of 9.1% 177 cases of death, sepsis mortality rate 35.3% (all 313 cases died, died of sepsis% of the total number of deaths 56.6%. Habitat death first). Therefore, the prevention of sepsis, to be taken seriously, do early prevention, early diagnosis and treatment. Burn sepsis occurred time and focus more on injury after three weeks. After three injury-7 days (edema absorption period), the first peak; Scabbed pm (10 ~ 20 days) for the second peak. The larger the area of burns, the more depth of burns, sepsis rates higher. Cause pathogenesis deep second and third-degree wound infection, sepsis often the main source, Compression is particularly moist wound infections, bacteria invade the bloodstream more easily. Followed by venous puncture incision or intravenous infusion into phlebitis infection, sepsis can also become a way. Clinical performance was mainly relies on clinical symptoms of early diagnosis. Hence the need for close observation of clinical symptoms of change, analysis of the reasons for the changes, seize the early symptoms of the following changes : ① temperature surging 39.5 ~ converted or unusual decline; ② the heart rate up to 140 times / and above, increased respiration, no other reasons; ③ psychiatric symptoms such as delirium, fidgety. David Cox; ④ anorexia, flatulence or diarrhea; ⑤ wound deteriorated, eschar change wet or deep Ⅱ degrees crusts see the size of the tip discharge or bleeding point, the continued increase in the number or gradually expanded, or wound granulation gloom and uneven, with a dark red spot necrosis; or have become living skin graft - was eroded by the invasion, not expand it to narrow. An examination, blood. WBC increased or decreased poisoning particles increased. 2, blood biochemistry. For a correct treatment of the wounds : Combat is one of the key systemic infection. Burn more stable shock soon after debridement, topical AgSD early exposure of the wound. Antibody shock at any time during the replacement of wet dressings and mattresses. 48 hours after the early emancipated, processed and evaporated wounds to prevent infection. Large areas Ⅲ degrees eschar for early excision and grafting is to prevent sepsis and active measures. 2, the rational use of antimicrobial drugs : antibiotics to combat infection is an important weapon, but the body must be able to play a role. Due to the increase in resistant rod, clinical some common antibiotics, the treatment of burn sepsis gradually lose value. and the need for a new generation of antimicrobial agents. Gram-negative bacilli such as an infection, pseudomonas, bacillus gas production, klebsiellar gun-alkali salt negative bacteria, citrobacter. can first use amikacin toxins, it vanguard, the new Green II, and other toxins. B-hemolytic streptococcus infection is still choose G. Green toxin. Carbencillin Green toxin on the role of Pseudomonas aeruginosa lower oxygen piperazine Green Pseudomonas toxin right, streptococcus faecalis, Proteus mirabilis a good antibacterial activity, particularly if either of the two drugs used to big. 3, the method of treatment, with no clear clinical diagnostic bacteriology and susceptibility results, can be isolated light wounds to the bacteria and antibiotic susceptibility results choice. Spend a long time ago, the amount due, diluted in 100 ml of glucose within the fluid or isotonic saline infusion, each given antibiotics alone. 2 ~ 3 antibiotics turn infusion, combination. The use of powerful antibiotics targeted, often in 24 to 36 hours could see initial results. Sepsis symptom control in a timely manner after the withdrawal. In addition, the removal of a colony of bacteria eschar, the incidence of sepsis higher before surgery, Surgical operation process and after surgery to intravenous antibiotics until after 3 ~ 4 days of systemic stability.

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