Chronic atrophic gastritis, anemia Why?

(1) chronic atrophic gastritis with pernicious anemia : A more in-atrophic gastritis, A study by the type of serum atrophic gastritis and gastric juice exist within factor antibody (IFA), its combination of block-and-one. Blocking antibody can block VitBl2 in the stomach and inner factor binding, the result can not absorb vitamin B12; and the combination of antibody with intrinsic factor-vitamin B1 two complexes combined. Factors within the lack of Vitamin B12 malabsorption resulting in the occurrence of malignant anemia. B-atrophic gastritis mainly involved in gastric antrum and gastric acid secretion in normal, Vitamin B12 absorption rare obstacle, it generally will not happen pernicious anemia. (2) chronic atrophic gastritis with iron-deficiency anemia : In addition to pernicious anemia, chronic atrophic gastritis can lead to iron-deficiency anemia, its causes are : ① main cell wall and cell secretion of gastric acid and pepsin of dysfunction, affecting food iron absorption. ② atrophic gastritis mucopolysaccharide have reduced the impact of inorganic iron in the gastrointestinal delivery, reduce iron absorption. ③ mucosa damaged for a variety of reasons due to the chronic blood loss. Hematopoietic materials (Fe) combined with the lack of chronic blood loss, it is extremely easy to create iron-deficiency anemia. In addition, chronic atrophic gastritis patients due to abdominal pain, anorexia, inadequate intake is one aspect of anemia caused factors.