Muscular Atrophy

Overview amyotrophic means rhabdomyosarcoma malnutrition, muscle mass than normal narrow, muscle fiber to small or even disappear, of the nervous and muscular disorders and one of the main symptoms. Muscle whether the nutritional status of normal muscle tissue depends not only on the pathological changes, and more closely related to the nervous system. According to have amyotrophic the original disease, amyotrophic General Clinical divided into three categories : neurogenic muscular atrophy, myogenic muscle atrophy and disuse atrophy. Cause pathogenesis neurogenic muscular atrophy common causes of disuse, nutritional obstacles, ischemia and poisoning. Frontier disease, nerve root, plexus, peripheral nerve lesions such excitement can cause nerve impulse conduction obstacles, so that part of disuse muscle fibers, have disuse atrophy. Other current motor neuron damage to any location, its peripheral location of the release of acetylcholine decrease Sympathetic where nutrition is diminishing muscular atrophy. Myogenic muscular atrophy by muscle disease, may also include other factors, or if the shoulder strap with facioscapulohumeral muscular dystrophy patients, confirmed by histological examination of the spinal muscular atrophy. Using microelectrodes technical inspection with muscular dystrophy animals showed functional denervated muscle fibers about 1 / 3. A clinical performance. Neurogenic muscular atrophy : because of lower motor neuron damage and caused. Anterior horn cells and brainstem motor neurons of nuclear damage was muscular atrophy segmental distribution was mostly in the distal limb, symmetric or asymmetric. not with sensory dysfunction, he often appears muscular trembling, muscle and tendon reflexes and the extent of the damage. EMG muscle tremor see potential or high amplitude motor unit potential. Biopsy see Muscular Dystrophy thinning. Beam microscope showed atrophy change. 2. Myogenic shrinking : from diseases caused by muscle itself. Not by shrinking nerve distribution, often with proximal pelvic symmetry and shoulder girdle muscular atrophy, and a few of the distal type. With decreased muscle strength, muscle fiber without tremor and sensory impairments. Serum creatine kinase and lactate dehydrogenase and aspartate aminotransferase, glucose phosphorylation modification enzyme, Aldolase so different levels increased muscle power kinase the most sensitive. EMG features changes to the short-time multiphase potential. 3. Other : Central muscular atrophy general with hyperreflexia or pathological reflex. Ischemic muscle atrophy caused by various arteritis, thrombus formation and ischemic muscle where aseptic necrosis. Disuse atrophy related to the long-term campaign. More than reversible.