Stones can cause cholangiocarcinoma?

Stones can cause cholangiocarcinoma, among them whether a causal relationship yes CHOLANGIOLITHIASIS and their families are most concerned about one issue. Biliary stones on the long-term stimulation, can cause bile duct wall of the inflammatory mucosal changes, and even the mucosal cell dysplasia. Therefore, it is generally believed that stones may have a certain relationship cholangiocarcinoma. Cholelithiasis is only caused by cholangiocarcinoma, or bile duct cancer in its development process with the gallstones, there is a controversial issue. There are many stones in patients, although the course is very long, and not turned into cholangiocarcinoma. Therefore, those with biliary calculi patients do not have too much tension, of course, we must not overlook the possibility of cancer and timely treatment at a hospital.