Tuesday, April 22, 2008
What nephrotic syndrome common complication?
(1) infections: from the large quantities of immunoglobulin lost in urine, plasma protein decreased, affecting antibody formation. Adrenal cortical hormones and cell poisons of the application of the patients decreased systemic resistance and prone to infections, such as skin infections, primary peritonitis, respiratory infections, urinary tract infection, and even induced sepsis. (2) coronary heart disease: patients with nephrotic syndrome often hyperlipidemia and high blood coagulation state, prone to coronary heart disease. It was reported in patients with nephrotic syndrome incidence of myocardial infarction eight times higher than normal. Nephrotic syndrome coronary heart disease has become the third cause of death factors (after infection and renal failure). (3) thrombosis: nephrotic syndrome patients prone to thrombosis, especially membranous nephropathy rate of 25% to 40%. There are several reasons why thrombosis formation of edema, less patient activities, intravenous stasis, high blood lipids, blood viscosity and increase the concentration, and high levels of fibrinogen v, Ⅶ, Ⅷ, x factor increased and the use of adrenal cortical hormone and blood-prone hypercoagulable state, such as. (4) acute renal failure: patients with nephrotic syndrome because of the large number proteinuria, hypoproteinemia, hyperlipemia, the body often in hypovolemia and hypercoagulable state ¨ District vomit, diarrhea, and the use of anti-hypertensive drugs Diuretics large diuretic, enable the kidney perfusion of blood suddenly reduced, thereby enabling lower glomerular filtration rate, leading to acute renal failure. Furthermore, nephrotic syndrome, renal interstitial edema, and protein concentration of plug formation of tubular and other factors, can also be induced acute renal failure. (5) electrolyte and metabolic disorders: the repeated use of diuretics or unreasonable to ban long-term salt, will keep patients with nephrotic syndrome secondary hyponatremia; adrenal cortex hormones and the use of diuretics, a large number of voiding a large number, if not timely Potassium, prone to hypokalemia.
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