Monday, July 7, 2008

What is the renal interstitial nephritis? How is it diagnosed ?

Tubulointerstitial an interstitial nephritis is a large group from various causes of kidney disease. Major violations of renal disease and kidney interstitial; clinical renal dysfunction to its outstanding performance. On the course, tubular interstitial nephritis an acute and chronic can be divided into two broad categories, according to the cause of the infection, drugs, and genetic immune mediated metabolism disorders caused interstitial nephritis, etc.. To clinical medicine who was the most common cause, followed by urinary tract obstruction with the complexity of the cause, pyelonephritis chronic. The main basis for the diagnosis: (1) patient medication history or have a history of chronic renal benefit Nephritis. (2) early in the disease, generally not field the ball the clinical features of the disease, Shuinazhuliu example, edema, hypertension, and so on, while renal dysfunction occurred in the earlier and with glomerulus hypofunction proportion. In addition, there are renal dysfunction but no high blood pressure, and a mild proteinuria, B2-microglobulin in urine increase. Given a tubular more than 90 percent of the cause of interstitial nephritis to rule, so early diagnosis essential, even for renal dysfunction have occurred in patients, if found and promptly handle the reversible factors (for example, urinary obstruction, Infection, etc.) can also suspend its development, and even improve renal.

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