Rh hemolytic disease of newborns which clinical performance?

Neonatal Rh hemolytic disease of clinical symptoms and the mother's anti - Rh antibody titer level of the closely related. About half of neonatal jaundice and anemia are very light, without treatment can be restored to normal. About 25% ~ 30% of neonatal body good, but mild to moderate anemia and mild jaundice, liver and spleen may be enlarged But no edema. If timely treatment, the prognosis is good; If no treatment or inappropriate treatment, jaundice soon, 2 ~ 5 days, Serum bilirubin can reach 20 mg / dl (342 μmol / L) above, it might be a nuclear jaundice. In sepsis, the enzyme poisoning, lack of oxygen or water loss under such circumstances, even if the serum bilirubin level above is not reached, can a nuclear jaundice. Kernicterus appear to be muscle relaxant, sucking reflex, and then muscle cramps, opisthotonus, and even convulsions. Difficulty breathing and bleeding often rapidly fatal. About 10% were likely to survive, but in the aftermath of brain injury, such as hand-foot-tic, nerve deafness and mental development disorders. About 20% ~ 25% fetal more serious illness. Pregnancy in 22 ~ 40 weeks between generalized edema, in the majority of intrauterine death, a few survive down, often premature. Anemia of prematurity is very serious, generalized edema, ascites, pleural effusion, significantly enlarged liver and spleen, skin and mucosa blockage points. Jaundice initially less significant, but developing rapidly and soon died. The main cause of death was liver dysfunction and heart failure. Maternal complications of pregnancy have polyhydramnios, preeclampsia. Stillbirths after secondary disseminated intravascular coagulation.