Friday, August 15, 2008

The elderly cirrhosis glucose metabolism disorders

The liver is the storage of sugar vary with the conduct of the main venues of Health, is to maintain a relatively constant blood sugar one of the major organs. Diffuse liver disease can be secondary to glucose metabolism disorders, showed impaired glucose tolerance or diabetes-induced liver. As the elderly liver and pancreatic morphology and function of the change to result in more Huangan Bing, glucose metabolism disorders. 1. The incidence of diabetes-induced liver principle of liver-derived diabetes may be related to the occurrence of liver enzyme (Glucokinase, glycogen synthase, hexokinase, FDP kinase) activity decreased insulin resistance increased concentration of hormones, insulin hypoglycemic effect of glucose And from high-sugar diet as a protective measure, glucocorticoid and the use of diuretics, chronic liver disease at the hypokalemia, and other relevant. 2. The elderly liver-derived diabetes the clinical features of the elderly often due to diabetes-induced liver cirrhosis of the clinical manifestations of chronic relatively prominent and covered up the symptoms of diabetes, or the emaciated, weak, dry mouth, low nutritional status, and other symptoms attributed to Liver disease. Some patients have significant dry mouth, and more drinking, more urinary symptoms. Because liver dysfunction, and more food is rarely see the performance of liver-derived diabetic ketoacidosis and nonketotic hyperosmolar coma are rare; retinopathy and neuropathy in a very low rate of cattle; compared with diabetes nephropathy Rare, and hypertension, atherosclerosis and the incidence of non-diabetic patients with cirrhosis same as the elderly, patients with diabetes than the primary low. 3. Treatment principle The elderly liver prototype focus on the treatment of diabetes treatment of liver disease is positive. Diet control can be properly angry sense of relief, in order to avoid inadequate nutritional intake. Although the elderly patients with cirrhosis of treatment, but often protracted course Buyu. In short cirrhosis elderly poor prognosis, the high mortality rate. Of elderly patients with cirrhosis should conduct a comprehensive and detailed inspection, done early diagnosis and treatment, organ function monitoring, prevention of failure, to strengthen support for therapy, rational drug use, to facilitate the extension of the patient's life.

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