Sunday, August 17, 2008

Hypertension will damage the kidney

Early in hypertension for some time, and will not cause significant kidney disease, only for the performance of high-sodium or blood volume expansion of the weakened ability to adapt, such as eating or drinking too much time Guoxian prone edema, high blood pressure. Since then gradually diluted concentrated in tubular function decline in performance for nocturnal enuresis increased, causing increased pressure within the glomeruli urinary albumin excretion increase. A few years later there may be mild to moderate renal arteriosclerosis, then renal ischemia, atrophy, fibrosis, kidney function gradually subside, the performance of the serum creatinine increase, with blood urea nitrogen and serum uric acid increased. In ischemic vascular endothelial kidney damage, kidney caused by the release of a series of the vasoconstrictor and vasodilative material balance disorders, have a material step-up increase, has been elevated to a higher blood pressure, high blood pressure and kidney between the "vicious Cycle. " With the increase of blood pressure and kidney beyond the control of the more severe atherosclerosis, can affect the tubular absorption, excretion, resulting in the creation or metabolism of some toxic substances can not excrete out, causing toxic accumulation in the body, known as uremia . Uremia chronic renal insufficiency is a serious stage, mainly for metabolites of retention, water, electrolyte, acid-base balance disorders and symptoms of systemic systems. Once patients with hypertension to uremia stage, not only to control blood pressure in an ideal level, but also through blood dialysis and peritoneal dialysis bitterness, who must be re-kidney transplant can save lives. So: a hypertensive patients should pay attention if they have swelling, increased symptoms such as nocturnal enuresis. These symptoms often prompt you: may already have early kidney damage, the need to timely treatment.