Patients with chronic pyelonephritis more often. Such patients may be due to a variety of incentives to attack again, there frequency, urgency, Niaotong, hematuria, and symptoms such as heartburn. Abnormal urine checks, urine culture can be found disease-causing bacteria. However, some patients with severe symptoms though, but the urine culture was not found. Clinically, this case is not uncommon, especially in healing or focal pyelonephritis, routine urine was sterile or low number of bacteria. Pyelonephritis when bacteria-free urine may be caused by:
① the most common causes for the anti-inflammatory drugs and the use of chemotherapy inhibited the activity of bacteria.
② side of the ureter obstruction, so that bacteria can not be discharged as urine.
③ urine acidity (pH value) of 5.0 or below a high degree of diluted urine (1.003 specific gravity in the following) is not conducive to the growth of bacteria.
④ rapid flow so that the bacteria have no chance to reproduce or slow the growth of bacteria or breeding is not easy.
⑤ there is a theory that chronic pyelonephritis as a aseptic disease, caused by the bacterial infection, after the disappearance of bacteria, and infected by bacteria or toxins continue to maintain the autoimmune mechanism.
