The relationship between diabetes and coronary heart disease

Diabetes is a systemic metabolic disorders, easily lead to coronary heart disease. The Framingham study showed that in diabetic patients, both men and women, different age groups, the incidence of cardiovascular disease are diabetic group than non-diabetic group. To gender, men are more the risk, but the age-adjusted and control other risk factors for coronary heart disease, diabetic women with the risk of coronary heart disease was significantly higher than that of men, some people even reported that diabetes is coronary heart disease in women An independent risk factor. Diabetic patients with coronary heart disease incidence rate of the reasons for the increase is not very clear, but diabetes easily lead to atherosclerosis has been recognized. Most scholars believe that obesity, hypertension, high LDL levels, high blood sugar, high-fiber protein hyperlipidemia (insulin resistance syndrome), these elements are inseparable. Obesity to the body to insulin resistance, in order to guarantee normal blood sugar levels, β-cell secretion to be several times higher than normal, or even several tens of insulin, a hyperinsulinemia, but also led to increased blood sugar, Elevated blood levels of triglycerides, HDL-C decreased, increased plasma fibrinogen, which are atherosclerosis risk factors. At the same time, insulin itself also has to promote atherosclerosis and therefore, oral hypoglycemic agents methyl urine categories such as insulin injections or through different channels so that blood insulin levels increase, which may further add to the hardening of vascular disease. In addition, patients with coronary heart disease, diabetes, coronary heart disease in some of the later onset of clinical symptoms or hide. Because of diabetic neuropathy can affect any part of the nervous system, especially the nerve endings, when the patient's damaged nerve endings, the pain threshold increased, even if a serious and myocardial ischemia, pain is not typical lighter emblem, or even No symptoms of angina, the pain of the high incidence of myocardial infarction and shock, heart failure, sudden death is also more complications, more serious prognosis.