The disease is caused by the varicella - zoster virus caused. The virus enters the body through the respiratory mucosa, spread through blood, appear chickenpox on the skin, but most people do not appear chickenpox infection is latent infection, with the virus were to become. The virus is neurotropic, sensory nerve endings in the skin can invade move along the nerve to the spinal cord dorsal root ganglia, and lurking in there, when the host's cellular immune dysfunction, such as colds, fever, When systemic lupus erythematosus and malignant tumors, the virus has been excited, resulting in ganglion inflammation, necrosis, while re-activate the virus can then move along the peripheral nerve fibers to the skin herpes. In a few cases, the herpes virus can be spread to the spinal anterior horn cells and visceral nerve fibers, causing the movement of nerve palsy, symptoms such as eye, facial paralysis and gastrointestinal and urinary tract.
VZV is a herpes virus, a neurotropic virus. Complete VZV spherical, diameter of about 150 ~ 200nm, a double-stranded nucleic acid is DNA, the regular icosahedral nucleocapsid composed of the outer layer is formed by loose lipoprotein envelope, interspersed with virus-encoded glycoproteins, viral particles only Shell is contagious. Chicken pox and shingles are two clinically different diseases but caused by the same virus. VZV original about 70 per cent of children in the clinical manifestations of infection after chickenpox, about 30% of human latent infection, both of which are those with the virus.
