Hyperhidrosis is due to sympathetic overactivity caused by excessive secretion of sweat glands of a disease. Sympathetic innervation body sweating. By controlling the sweating heat sympathetic to regulate the body's temperature under normal conditions. But the sweating and facial flushing, hyperhidrosis patient completely lost the normal control. Sweating and facial flushing patients in frustration, anxiety or panic daily.
1. divided according to the situation sweating
1) the limitations of hyperhidrosis: often the beginning of mood swings older teenagers, 25 years later there is a natural tendency to mitigation. The most common site is the limitations of palmoplantar hyperhidrosis and friction surfaces, such as the armpits, groin, perineum. Followed by the forehead, nose and chest. Palmoplantar hyperhidrosis can be persistent or transient, caused by mood swings, no seasonal difference, often cold hands and feet even cyanosis, falling may be associated with hand, foot and keratosis performance. Axillary sweating or mental activity may be due to heat induced. Armpit sweat excessive sweating is due to small-induced, unlike the main cause of underarm odor in apocrine.
2) generalized hyperhidrosis: mainly due to the extensive body of other diseases caused by sweating, like high fever infection due to the regulation of the nervous system or oral antipyretic sweating to dissipate the heat. Like other damages the central nervous system including the cortex and the basal ganglia, spinal cord or peripheral nerves can cause systemic hyperhidrosis.
Generalized hyperhidrosis is difficult to control, focusing on the treatment of diseases associated with the foundation. Palmoplantar hyperhidrosis mainly to local treatment. Axillary hyperhidrosis treatment is often not as good as palmoplantar hyperhidrosis.
1. drug treatment
1) conventional antiperspirant external use include 20% to 25% solution of aluminum chloride, aluminum acetate solution was 0.5%, 3% to 5% formaldehyde solution, 5% alum solution, 5% tannic acid solution. The number of drugs outside use too much, it will cause localized dry chapped mild or severe irritation.
2) systemic drug treatment for hyperhidrosis is mainly related to the primary disease. Sedatives (phenobarbital, amobarbital, secobarbital, chlorine beauty bar ketone, etc.), and a small dose of anti-anxiety drugs (diazepam, hydroxyzine, Dorset equality) of emotional hyperhidrosis effective. Large doses of anticholinergics to inhibit the secretion of sweat, dry mouth can cause unbearable, it tends to be eliminated.
3) Physical Therapy tap water iontophoresis therapy, applied topically (palms and soles, armpits) topical treatment failure patients. Install pacemakers were banned. Shallow X-ray irradiation can inhibit the secretion of sweat glands, only apply to other treatment failure severe palmoplantar hyperhidrosis patients.
4) botulinum toxin A (BTX-A) injection used for the treatment of palmoplantar and axillary hyperhidrosis. Usually 5 to 7 days after injection clear antiperspirant, can maintain an average of 9 to 12 months.
2. Surgical treatment
Selective removal of the second to fourth thoracic sympathetic of palms, armpits, chest and facial hyperhidrosis have a significant effect, but not for patients with plantar hyperhidrosis. And surgery can lead to permanent anhidrosis and other parts of the compensatory sweating, it should be used with caution. Only axillary hyperhidrosis, can be selectively removed underarm sweat glands secrete most active part, this method has a positive effect.
