IgA nephropathy outlined diagnosis

IgA nephropathy is a group of more than cause immune from the same characteristics of the pathology of chronic glomerular diseases. Clinical about 40% to 45% of the patients presented with the naked eye or under the microscope hematuria, 35% to 40% of the patients showed proteinuria with microscopic hematuria, and the remaining performance nephrotic syndrome and renal failure. IgA nephropathy is a common worldwide glomerular diseases, and its prevalence in different continents, different countries or in different regions of a country very different, such as Asia, Japan, Singapore, the incidence of IgA nephropathy of the Primary glomerular disease by 50%, but the western United States, Indian low-only two percent. Generally speaking, white, yellow, significantly higher than the incidence rate of blacks. China IgA nephropathy accounts for the incidence of the primary glomerular disease 26% to 34%. Male to female ratio is about 2:1. Hematuria mainly to the effects of IgA nephropathy At present there is no treatment. As the disease pathological type and glomerular damage greater degree of difference. Therefore, patients should be closely observed gross hematuria attack frequency, the degree of proteinuria, hypertension and renal dysfunction there extent, and were taken appropriate prevention and control measures. Clinical manifestations 1. Attack gross hematuria, 2. Mild proteinuria, most of <1 g / 24 hours, 3. Hypertension; 4. Other manifestations such as a uremic may have uremia clinical manifestations. Diagnosis 1. Occurred in the upper respiratory tract infection or gross hematuria or asymptomatic microscopic hematuria and proteinuria (especially young men), 2. Hematuria for glomerular (mainly deformed red blood cells), proteinuria is high, medium or elements Mixed proteinuria, may be elevated serum IgA 3. biopsy immune pathological examination mesangial area can be seen mainly IgA granular Immunofluorescence 4. except streptococcal infection after acute glomerulonephritis, non - IgA mesangial proliferative glomerulonephritis, thin basement membrane nephropathy, lupus nephritis, Purpura Nephritis, cirrhosis of the liver and alcohol-induced liver disease, such as kidney damage.