Wednesday, March 12, 2008

Chronic lymphocytic thyroiditis

Cause pathogenesis has not entirely sure, but most scholars believe that the disease as a home autoimmune diseases, typical lymphocytic thyroiditis sometimes with other diseases exist at the same time, such as toxic goiter, myxedema. nodular goiter or thyroid cancer, and so on. Clinical manifestations of the disease were seen mainly in middle-aged women and minorities after the onset patients without any symptoms, most of the patients neck discomfort. Occasionally difficulty breathing or swallowing difficulties, severe local pain and tenderness. a few cases early in the course of disease can be mild hyperthyroid performance, and most of the latter part of the course but is a low performance. Early course often diffuse goiter, a isthmus most significantly, soft texture volatile than the surface formation, but later the entire thyroid may be showing a nodular. Even shrink, and there myxedema. Diagnostic laboratory tests : basal metabolic most normal or low ESR fast, plasma albumin appearing reduced and gammaglobulin increased. Said the body may have a high thyroglobulin exist. As the hemagglutinin (titer "a ~ 160) and enzyme-linked immunosorbent assay (in a 50-over) were detected. certain diagnostic value. Treatment can be done thyroid replacement therapy formulations, a prostaglandin tablets daily 120 ~ 180 mg, such as more rapid onset, Patients with localized tenderness obviously, will be replaced it immunosuppressants, such as strong pine, daily 15 ~ 30 mg. To the late lesion, such as more visible goiter, thyroid replacement therapy can not be restored to normal and there tracheal compression symptoms, can be done thyroid isthmusectomies to remove oppression

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