Recurrent aphthous

Recurrent aphthous outlined oral mucosal disease is the most common disease with recurrent and self-limited, also known as recurrent aphthous ulcers. Cause pathogenesis of the disease etiology and pathogenesis is unclear, and may be immune dysfunction, genetic, gastrointestinal dysfunction, endocrine disorders (some women and the incidence of menstrual cycle), mental stress, lack of sleep, certain lack of vitamins and trace elements, infection, and so on. Clinical manifestations (1) light (small) RAU : The most common type, good fat lips, cheeks, tongue, floor of the mouth and other non-keratinized mucosa, gingival rare and hard palate. Small lesions began to congestive point, a partial burning sensation, and then expand the lesions, superficial ulcer formation. Ulcer typical round or oval-shaped, 2-5mm in diameter, slightly subfoveal surface covered by a layer of light yellow ensued, Congestive around mucosa was red-pain Obviously, the impact of words, eating. Ulcer usually lasted 7 ~ 10 days may be dead self-healing, self-limited said, after healing without leaving scars, but also a time lag recurrence, Recurrent said, the two said during the onset of intermittent period, the length of intermittent periods, each different in the ever-recurrent process, Intermittent progressively shorter period, even without intermittent period, ulcers waged continuous. Ulcer small number, about 1 ~ 5. (2) heavy (large) RAU : also known as the recurrence of this type of necrotizing peri - mucosa (Periadenitis.Mucosa Necro ti-ca Recurrens, PMNR) or adenovirus weeks aphtha. This type of rare, ulcers huge and profound in diameter up to 10 ~ 30mm. Deep and submucosa of the mucous glands or glandular tissue, ulcer-end hardware, and micro-edge missing significant uplift (Map 3), After healing often left scars, ulcer pain than drama, the course could be as long as several months or more, but there is still self-limited, recurrent, This type of oral ulcers from the previous backward in the development of the tendency for many years after attack by the frequent occurrence of ulcers in tongue arch palate, soft palate, Suspended Yong volume location, a number of ulcer-two large ulcer, or around several small ulcers, patients of a good body. This type of ulcer may well occur, ulcers features recurrence, self-limited, Systemic and biopsy and specificity of ulcers or tumors. Map 3 Recurrent aphthous ulcers (3) herpes - like stomatitis : I inflammatory also known as aphthous ulcers, herpes - like aphthous ulcers. Characteristics of this type of ulcer number, up to tens or even hundreds, scattered in the oral mucosa of any location in ventral tongue, I was mostly in the end. Ulcer smaller diameter only a ~ 2mm can be blended into a larger ulcers, congestive around mucosa, ulcers sustained 7 ~ 14 days. lighter Aphtha intense pain, headache individual patients fever symptoms. Besides, there is a recurring oral ulcer disease, the first in 1937 by the Behcet's reports, called Behcet's syndrome (Be-hcet's Symdrome), the four major symptoms of oral ulcers, the type of recurrent aphthous ulcers may arise; eye symptoms are recurring iridocyclitis. or a combination of the former empyema uveitis; Symptoms of genital outer genital and perianal skin or mucosa occurred isolated and small ulcer pain, mainly in the male scrotum, glans penis, penis, women mainly in the size of the labia minora and other parts; skin may appear erythema nodosum, folliculitis, Acupuncture was developed at the injection site reaction; It can still some minor symptoms such as large limbs arthritis, gastrointestinal ulcers, may irreversible cardiovascular, nervous system, lung, genitourinary system, the symptoms may not appear. and oral lesions often is the first to hold. Treatment (1) systemic therapy : should, as far as possible to identify some general factors to be eliminated and the factors relating to the treatment. 1. BRM : If levamisole 50 mg, 3 / d for 3 days, 11 days of withdrawal, repeated six times for a course of treatment; Transfer Factor medial arm 2 ml subcutaneously, 2 / w, 20 for a course of treatment; Thymosin 2ml intramuscular injection, qod, 15 for a course of treatment. 2. Immunosuppressant : corticosteroid for a heavier attack without contraindication to the other patients, High-5 ~ 10 mg, 3 / d or dexamethasone C'attle, 3 / d, oral 3 ~ 5 days after control of the disease can be gradual reductions; cyclophosphamide and azathioprine 25-50mg, 3 / d; THH 500-tment of advanced esophageal, 3 / d. 3. Other : various supplementary vitamin B, C, E, folic acid, zinc or iron deficiency if, or iron or zinc agents. 4. Chinese dialectical therapy : can be given Qingre Xiehuo, cools the blood purge, Yangyin Qingre, Yiqi spleen, and stomach Qingre such prescriptions. (3) local treatment : anti-inflammatory painkillers can promote healing of ulcers. 1. Film : If local Application chlortetracycline, Spiramycin, norfloxacin, rifampicin, wash it too, estrogen and other film. 2. Gargle Exposure agent : 0.2% if it is too washing liquid, or 2% tetracycline aureomycin Gargle. 2.5% aureomycin glycerol Exposure; such as ulcers, severe pain with 1% procaine liquid mouthwash can be painkillers for a few minutes. 3. Exposure of Chinese medicine powder : If Kuiyangsan Xileisan, BINGPENGSAN POWDER BY etc.. 4. Glucocorticoids : As the High - or to the use of triamcinolone acetonide and 1% procaine on the 0.5-1ml injection lesions, a / w can also be used with all of the tablet, paste, such as sprays. 5. Corrosive : sporadic individual small ulcers in an early ~ 2% tetracaine liquid surface anesthesia, using probes sharp dip in a little 50 ~ 100% TCA, or 10% silver nitrate, ulcers point in the center, to be ulcer-gray immediately after the show probe, ribs can be. 6. Helium vapor laser illumination.