Lymphatic sarcoma diseases outlined

Lymphatic sarcoma rare, accounting for brain tumors 0.8 ~ 1.5 percent, adult males (50 ~ 60 years) higher incidence. A malignant lymphoma, mesh cell sarcoma, malignant proliferation of mesh, mesh cells of the brain, not typical granulomatous encephalitis, lymphoproliferative disease, and other names. This reflects the organization of a school and histological still insufficient understanding. This tumor etiology is unknown, most of that occurred in the surrounding blood vessels undifferentiated multipotent cells, as some factors (such as trauma, antigen) stimulation, the cells differentiate into blood cells, including lymphocytes and may develop into lymphatic sarcoma. In recent years as a result of the kidney transplant operation, and application of immunosuppressant with acquired immunodeficiency disease (Aids) increased, resulting in anti-tumor immune surveillance weakened, enabling of this occurred, appeared to be increasing trend. Tumors were single or multiple. Distributed in the basal ganglia, the corpus callosum, periventricular, thalamus, cerebral hemisphere white matter and brainstem and other places, a few may infiltration dura, arachnoid. Shorter spindle tumor cells and vascular center arranged for a wreath-shaped, or cuff-like cluster growth, resulting in vascular intracavity thinning, occlusion, a focal hemorrhage and necrosis. Center for follicular cells of B-cell, sometimes visible plasma cells. Rich reticulocyte fiber separation tumor cells. PAS staining Visibility Russell bodies. Karyokinesis phase, nuclear containing vacuoles and prominent nucleoli. Often tumor hemorrhage, necrosis, along subarachnoid disseminated. Disease symptoms with different size and location vary. Often headache, nausea, vomiting, and other symptoms of increased intracranial pressure and other focal symptoms. Most cases of the slow growth performance for the organ brain syndrome (Organicbrain syndrome) or demyelinating lesions. Minority performance for the type of influenza encephalitis, began to have fatigue, headache, neurological symptoms after. Some can be a tumor on its own narrow cyclical, edema alleviate symptoms and ease the biological characteristics. Increased cerebrospinal fluid protein content, sugar decreased, increased lymphocytes, tumor cells can be found. Indirect immunofluorescence using polyclonal antibody peroxidase or technical inspection, cell surface may show monoclonal immunoglobulin light chain (K or λ), most patients beta-2-microglobulin increased, myelin basic content increased, β - glucosidase acid enzyme increased IgA reduction. The diagnosis of malignant brain tumors and other difficult to identify, finally confirmed by pathological examination to be determined. CT scan: scan can show clear boundaries, such as density or slightly higher density video, volume more> 4 cm in diameter, at a sustained phyllodes tumor necrosis within a small area, the surrounding brain tissue edema operations, after the injection of contrast agent showed high tumor Uniform density increase. Sometimes a central low-density, around a circular enhanced, similar brain abscess.