Primary pulmonary tuberculosis in the pathogenesis

Primary tuberculosis refers to the initial infection caused by Mycobacterium tuberculosis disease. Tuberculosis infection in China is about 80-90% lower respiratory tract infection through the lungs, Tuberculosis generally is therefore essential that primary pulmonary tuberculosis. It generally includes direct progress after infection caused by disease, namely primary syndrome, tuberculosis and their mediastinal lymph nodes caused by lung disease, such as bronchial pneumonia, and leaves empty formation of lesions. Tuberculosis infection caused by the initial limitations of small lesions bronchial pneumonia, lung ventilation was particularly prevalent in the better part of the bottom of the above, the middle of the upper or lower leaf, and often near the pleura; mostly individual. It will soon happen cheese - like change, then by fiber parcels. LOCA cheese - like substance, calcification, ossification and even healing. In the primary lesions in the course of forming bacteria through the lymphatic to hilar lymph nodes, lymphatic caused inflammation and lymphadenitis, the latter also occurred cheese - like change. The primary pulmonary lesions, lymphatic and local lymph node lesions, a primary SARS.
Most primary tuberculosis infection can automatically heal, whether the disease after infection with the human immunodeficiency. Younger, low resistance, the more opportunities for pathogens; plus miscellaneous respiratory infections such as measles, influenza, whooping cough, and other more easily and lesions caused morbidity and progress. Adults initial infection tuberculosis, in a non-immune status, may also cause primary tuberculosis. The primary cause of SARS may be a deterioration of primary pulmonary lesions progress, bronchial pneumonia and tuberculosis, and the occasional empty liquefied form of bronchial lesions disseminated. The hilar and mediastinal lymph nodes progress more common, the cheese - like lymph nodes change to continue to develop the surrounding lymph nodes caused inflammation; lesions can be directly or through lymphatic spread to a nearby lymph node. Cheese-like lymph nodes to the bronchial compression or rupture, causing bronchial pulmonary tuberculosis and their changes, such as atelectasis and obstructive pneumonia. Lymph node tuberculosis rupture into the bloodstream, the bacteria enter the blood circulation, causing varying degrees of blood type disseminated.
Primary tuberculosis infection symptoms minor and short-lived, many children unknowingly After this infection. Sometimes in the primary TB allergic increased syndrome, such as erythema nodosum, multiple arthritis; and with of mild to moderate toxicity symptoms, such as malaise, anorexia, height ranging from fever for a period of 2-3 weeks or longer.
Primary tuberculosis often no obvious signs, and if pulmonary atelectasis real change,heard voiced, respiratory bronchial tone was breathing or reduce the sound. Bronchial obstruction part Wheezing can hear the sound. Extensive formation of bronchial pneumonia or empty, wet Luo Wen Yin.