Sexual system sclerosis kidney damage TCM treatment?

Drug treatment should be to the extent of kidney damage, to adopt a method of treatment. Ⅰ (subclinical damage type) : This period is characterized by patients without proteinuria, hypertension and azotemia, renal plasma flow, Renal biopsy typical histological changes, abnormal vascular reactivity and plasma renin activity can be increased. Prevention is the main treatment and avoid various renal blood flow to enable a further reduction of factors such as heart failure, bleeding, dehydration, temperature Down. be appropriate application of vasodilator drugs, but also a useful role to be confirmed. Phase II (clinical renal damage in type) : Characteristics of patients significantly hypertension, proteinuria and azotemia. Some patients increased plasma renin activity, renal function remained stable or slow the development of kidney failure. Treatment including control of blood pressure and renal plasma flow to maintain. Hypertension with increased plasma renin activity, the choice of converting enzyme inhibitors such as captopril, from 12.5 mg per day, gradually increasing dose, the largest available daily to 150 mg. It may be appropriate application of diuretics and calcium antagonists. Hypertension and plasma renin activity were normal, should be combined vasodilators and diuretics. that could be necessary with beta-receptor blockers or methyl dopa, but the beta-receptor blockers may increase Renault, It should be noted. If this view of the existence of the following crisis-prone renal syndrome : ① disease early thickening of the skin; ② anemia; ③ pericardial effusion or congestive heart failure. It was argued that for these patients, even in the absence of hypertension, can also give vasodilators or converting enzyme inhibitors for the prevention, But there is no documentary evidence to support this practice. Phase III (renal syndrome crisis) : This period is defined onset 3 ~ 4 years of the following : ① sudden sharp increase blood pressure; ② plasma renin activity in the normal two-fold; ③ rapid deterioration of renal function; ④ exudative retinal retina cotton-wool patches or bleeding. Crisis renal syndrome is a threat to the life of patients with serious complications, often in a few days or weeks of heart failure. hypertensive encephalopathy, end-stage renal failure, it must be actively addressed. Treatment is the key to controlling blood pressure can be combined converting enzyme inhibitors, potent vasodilators, diuretics, etc.. Usually after controlling blood pressure and renal function can be improved or stabilized and retinopathy improved. Some patients even if blood pressure is under control, but is still carrying out renal function deterioration, ultimately requiring dialysis treatment or kidney transplantation. If unable to control hypertension drug, the patient's condition worsened, it would OK dinephrectomy resection to hypotension. Ⅳ (terminal renal failure phase) : The treatment depends mainly on hemodialysis and renal transplantation. Scleroderma is generally believed that more small vascular lesions, peritoneal dialysis may be adverse effects. Anticoagulant and antithrombotic drugs is not yet clear, it was considered probation; Hormones on the skin and visceral lesions limited, right kidney damage invalid, but some scholars try corticosteroid and cytotoxic drugs for 6-12 months.