Saturday, March 1, 2008

Antibiotics like penicillin can hurt liver

Antibiotics are not necessarily higher than other drug side-effects, but its use of the opportunity to use the crowd-and, therefore, there is some side effects can affect many patients. Among them, antibacterial drugs on liver function is the need attention. The following examples of antibacterial drugs (both GM) has caused liver dysfunction reported, although rare, but should also pay close attention to the use of the process, when necessary for liver function tests. In particular, there liver dysfunction should be used cautiously. Penicillin natural-synthetic penicillin than penicillin (such as amoxicillin, ampicillin, piperacillin) - induced liver dysfunction rare. Penicillin-induced liver dysfunction mainly after treatment for fever, and other allergic skin redness phenomenon. Such cases should immediately check liver function. If abnormal, immediately switch to other antibacterial agents. There was amoxicillin / clavulanate potassium mixture can cause severe liver dysfunction, which may cause death. Cephalosporin allergy caused by liver dysfunction. Clinical rare, mild reaction, there will be short-term elevated transaminase. But so far by the use of cefazolin, Ceftezole Sik Cefmetazole require hospitalization caused by liver dysfunction in patients. Reports that ceftriaxone can cause severe liver dysfunction. Tetracycline intravenous more than 1.5 grams, a considerable number of patients, there may be liver dysfunction, particularly in patients with renal dysfunction more dangerous. Few long-term oral tetracycline can cause liver dysfunction, and continuing jaundice induced by the drug occurred within five weeks (long-term use of tetracycline attention to the treatment of adult acne). More than one drug, there is an autoimmune hepatitis risk. In addition, according to the World Health Organization reported that the use of minocycline hydrochloride (minocycline), 6% of the people there liver dysfunction occurred in 3 weeks after the administration of several months. Erythromycin has liver dysfunction relatively rare, such as occurred in more than a few days after treatment to post on the 20th. Quinolones extremely serious liver dysfunction occurred in the early phase of treatment. Aminoglycoside antibiotics cause liver dysfunction were rare, individual circumstances such as amikacin, gentamicin, kanamycin and tobramycin has caused liver dysfunction reported.

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