Children with aplastic anemia in the diagnosis and classific

Children with aplastic anemia diagnostic criteria for : [1] blood cells, reticulocyte absolute reduction. (Eg two-reduction, which must be reduced platelet). [2] General without splenomegaly. [3] bone marrow at least part of a proliferation of reducing or severe reduction. [4] except for all other blood cells to reduce diseases, such as paroxysmal night Hemoglobinuria, MDS, acute lymphoblastic leukemia. [5] General anti-anemia treatment ineffective. Type : [1] acute aplastic anemia (AA severe type 1) : ① : rapid onset, anemia sexual heavier accompanied serious infection, and bleeding. ② blood : In addition to a decrease in hemoglobin must possess the following three were two : hi reticulocyte <1%,> 70%. Membership bone marrow biopsy showed bone marrow hematopoietic cells arabica Africa has markedly increased. [2] chronic impaired : ① : slow onset, anemia mild to moderate infection were less bleeding. ② blood : reticulocyte, WBC and platelet three at least two lower. ③ marrow as : office, two - or three-reduction, which must be megakaryocytic lineage lymphocytes increased> 30%. Membership bone marrow biopsy showed bone marrow particles increase in the non - hematopoietic cells. [3] severe aplastic anemia Ⅱ : If chronic illness impaired acute exacerbation, reticulocyte, WBC and platelet significantly reduced compared with severe aplastic anemia Ⅱ.