Wednesday, March 5, 2008

Breast Fibroadenoma pathological manifestations

Breast Fibroadenoma the specimen can be found at : fibroadenoma and the surrounding breast tissue boundaries clear, activities, materials and tough. smooth surface. Tumors formed round or oval, the surface often integrity of the thin fibrous capsule. When more fiber components, the cut surface of tumor gray and white, translucent, texture tough, resilient; When his rich epithelial component, the cut surface light pink belly, fine particles, and even showed papillary, outbound pulls out, soft texture. Breast Fibroadenoma in optical microscope, under its fibers and the growth of epithelial component level and the structure of mutual relations, into tube type, the tube and mixed three types of pathology. (1) Tube Type : interstitial proliferation of fibrous tissue oppression cells, it elongation, bending and deformation, seem to be serious interstitial elements penetrated within the lumen. Tubular epithelial shrinking by squeezing into flat. Tumor tissue than osteoporosis, showed myxoid. (2) weeks of types : epithelial components and fibers mixed together, the risk was circular, oval or irregular in shape hyperplastic tissue from the extrusion. Luminal epithelial cells have two components, the inner layer of single-cube or columnar epithelium, the outer layer of translucent cytoplasm myoepithelial. Its components epithelial hyperplasia can be mild. Tumor fibrous tissue hyperplasia and around the tubular around, loose or tight, even with collagen denaturation. (3) mixed : pipe and tubular weeks of the pathological changes also exist.

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