Chemotherapy blood system toxicity

Hematopoietic cells mainly in the bone marrow cavity of red bone marrow. Blood system to chemotherapy drug toxicity is erythrocyte, leukocyte and platelet production decreased as the main performance, it can also be considered as bone marrow inhibition. Chemotherapy drugs can inhibit the growth cycle immature stage of the cell group, it is of the departments naive blood hematopoietic cell destruction. When some mature blood cells Zhongyuan life done, and the bone marrow growth of the new generation of blood cells was chemotherapy drugs and the destruction of irreplaceable supplementary mature blood cells, the clinic that is, the performance of abnormal blood cells. Erythroid abnormalities such as when the patient is weak, looking pale and activities lightheadedness, shortness of breath, chest pain, severe vertigo may have, such as anemia symptoms collapse; The Department of abnormal white patients vulnerable when accompanied by high fever and lung, skin, urinary tract and other tissues and organs symptoms of the infection; Macrophage abnormal, the patient will have no degree with the bleeding. If bleeding gums, nose bleeding, ecchymosis, menorrhagia, can occur serious hematuria, blood and then other cerebrovascular accident. Laboratory examinations revealed : erythrocyte, leukocyte and platelet volume reduced. Can cause hematopoietic system toxicity of drugs : vincristine, cyclic plastic stream, the source of the gold (6 a source of the gold-dredging), A sugar Cellular Music, A Butterfly moan ammonia (ammonia A Butterfly moan), daunorubicin. Busulfan (busulfan), such as hydroxy veins