The treatment of childhood leukemia

Childhood leukemia research and treatment of the latest Currently, many of the world's Medical Center, University Hospital and the Institute are related to leukemia causes, diagnosis and treatment research. (1) genes DNA scientists in understanding the changes that will cause cell and bone marrow stem cells to develop into leukemia this point is making significant progress. The frequent occurrence of leukemia in gene dislocation of further understanding, we can make even clearer : Why is the growth of these cells will lose control, and why they did not develop into in the normal activities of the mature cells. Such knowledge can be used for the development of gene therapy. Using gene therapy to replace the normal DNA abnormal DNA in cancer cells, thus restoring the cell's normal growth control. By changing the DNA of leukemia research, doctors have been able to use high-precision test methods used to check the disease. For example, the polymerase chain reaction will be adopted leukemia gene dislocation or restructure to identify them. Such examination from one million normal cells found in a tumor cell. It can be used for treatment of the complete eradication of leukemia, in order to take decisions that do not require further treatment. (2) Clinical Trials Several important issues ongoing clinical trials, including : Why 30% of acute lymphocytic leukemia (ALL) in children will relapse, and how to prevent? Whether a harbinger of higher sensitivity factor can be used to identify the need for further intensive treatment to the children? To enhance chemotherapy can be more effective for the treatment of acute myeloid leukemia cells, and using growth factors to help restore normal bone marrow children? Resistance acute myeloid leukemia chemotherapy drugs reversal? It is not used for the treatment of leukemia better drug? Drugs, toxins or radioactive antibodies can be passed, only targeted leukemia cells? Antibodies used to select leukemia, and then use drugs, toxins or radiological sabotage it. Can a natural "biological response that agent" to help the body's immune system resistance of leukemia cells? No. 9 and No. 22 chromosomes misplaced children cured prospects? With this particular dislocation leukemia cells of children cure rate is very low. Currently, a devoted to such dislocation cells kill the drug undergoing clinical trials. Childhood leukemia after treatment needed attention to the problem After treatment within a few years, then the routine examination is very important. Doctors will continue to monitor the conditions and treatment of short-term and long-term side effects. The incubation period is very long treatment of complications, including heart damage, reproductive ability or infertility, the lower scores and the second trigger cancer. Chemotherapy may also cause other complications, doctors and patients before treatment started very carefully. After Leukemia Treatment includes a careful examination of the physical examination, laboratory tests, X-ray examinations. These inspections are usually once a month the first year, second year, every two months, and the third year, every three months, every six months until the fifth year. Five years after the child is best to see a doctor each year. Leukemia relapse usually occurs in the course of treatment or shortly after the end of treatment. Acute lymphocytic leukemia or acute myelogenous leukemia, if after the end of treatment in the first two years, not a disease Katherine, after the possibility of recurrence was small. After treatment, care benefits is to let the parents are concerned about their children opportunities for rehabilitation process of emerging issues. Once the emergence of new symptoms, the children or the parents should immediately tell doctors, which can effectively deal with relapse or side effects. The side effects of leukemia treatment Children leukemia after treatment, decreased ability to learn. This may be due to the head of radiation and chemotherapy spinal fluid reasons. Generally, the situation is very minor and would not result in disability. Young children than older children more vulnerable to impact. Other organs such as the liver, kidneys and heart may also be chemotherapy damage, but will not interfere with the child's normal activities. If children use a certain form of chemotherapy drugs such as podophyllotoxin and alkyl compounds, there is suffering from other forms of leukemia remote possibility.