Clinical features of acute leukemia

(1) leukemia cell infiltration affect the normal hematopoietic cells generated by the performance of the clinical symptoms and signs:
1. Fever: Common symptoms of this disease. Multi-low heat of fever, often as high fever caused by infection. The site of infection is usually oral, respiratory tract, urinary tract, and perianal skin.
2. Hemorrhage: can occur in any part of the skin and mucous membrane, can be a visceral serious bleeding or even fatal intracranial hemorrhage.
3. Anemia: The great majority of patients have varying degrees of anemia. Performance is looking pale, dizziness fatigue, palpitation shortness of breath, and so on.
(2) bone marrow infiltration of leukemic cells in organs other than the signs:
1. Liver, spleen, lymph nodes: hepatosplenomegaly the disease is more common signs, or about 50 percent; lymphadenopathy can be as high as 90 percent to ALL for the common, followed by single-urgent, urgent again tablets.
2. Bone and joint pain: sternum tenderness is a diagnosis of the disease the signs. The location and more pain in bone and joint occurred, a migration of local non-red, swollen, hot phenomenon. In addition, a small number of young patients with acute tablets of the flat bone tumor, there will be green, for the quality of its features and hardware connected with the periosteum, the mass was green,may green.
3. Skin and facial performance: skin visible, nodules, tumors, dermatitis; swelling gingival bleeding, oral ulcers and pharyngodynia to single urgency for the obvious. The green eyes of multiple sites to exophthalmos of the main performance, re-emerging ocular paralysis can be blind.
4. Other: the central nervous system due to infiltration and bleeding, there will be increased intracranial pressure and cranial nerve damage, also cocoa peripheral nerve involvement. Pericardium, myocardium and endocardium can be invasive, but there are clinical manifestations are rare, can be in terms of pericardial effusion, such as heart failure and abnormal heart rate. Bronchus and lung may be leukemia cell infiltration.