Wednesday, March 5, 2008

Clinical manifestations of chronic lymphocytic leukemia

I. GENERAL symptoms
Implicit attack onset, slow progress in the tumor itself can cause fatigue, weakness, weight loss and other symptoms.
Second, infection
Because of immune abnormalities in immune dysfunction and various infections, the most common respiratory infections, skin, gastrointestinal tract, urinary tract, such as sepsis.
Third, liver and spleen lymphadenopathy
Superficial lymph nodes slow leaching is the most common signs, with the condition progress from small to large and small increase, from local to the whole body. Enlarged lymph nodes smooth surface without adhesive, activities, hardware texture, no tenderness, and other characteristics. Abdominal lymph nodes can cause abdominal pain, mediastinal lymphadenopathy can cause coughing, Qingya and breathing difficulties. For more than mildly enlarged liver, splenomegaly than slow tablets obvious.
IV, skin damage
About 10% of the patients will have skin damage, were scattered in red or purple, leukemia cells in the skin caused by infiltration. There are also non-invasive skin damage such as skin itching, pigmentation, erythema, exfoliative dermatitis and herpes zoster.

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