Wednesday, March 5, 2008
Overview of bone fibrosarcoma
Fibrosarcoma of the lowest incidence rates, or about Bone Health sarcoma 1 / 5 weak. Primary fibrosarcoma of bone can be divided into two types with the surrounding Center. Central endometrial occurred from bone, the surrounding bone from the outer membrane of occurrence of peripheral tumors sometimes difficult and soft tissue tumor within the fiber of identification. Another part of secondary tumors in giant cell tumor of bone, bone deformities inflammation, proliferation of abnormal bone fibers. This type of secondary bone fibrosarcoma with fibrosarcoma of bone identification. Due to the slow development of the former, the better prognosis, the treatment of the two should be different. 【Fibrosarcoma of bone pathology - occurred in the outer membrane of soft tissue tumors were larger and the destruction of bone tissue later and less. Endometrial occurred in bone, the marrow of their average from top to bottom and around the development, so bone defects caused by the earlier and extensive, but not soft tissue tumors often significantly. Long bone or backbone of the metaphyseal bone may occur fibrosarcoma. The skull, jaw and spine of fibrosarcoma not uncommon, when a skull tumor, bone deformities inflammation may change. The naked eye observation that there is a false fibrous tumor cyst, section for the hard shiny white organizations, some of calcification may occur or tumor necrosis and a gray and white or yellow or false cyst-like. Soil under the microscope that its mast must organize the ingredients for nuclear staining deep spindle cells, in the minor constituents of the spacious circular or stellate cells, can be part of a transparent tumor tissue degeneration or mucus-like degeneration and necrosis and calcification phenomenon. The reaction of a very small amount of new bone biopsy occasionally can be found, but no bone tumors exist. There is a small part of the main organizations for the tumor shape, size, staining consistent with the small-vector form closely posed by the cell, fewer mitotic figures, called spindle cell sarcoma, it is of a fibrosarcoma of bone, no separate name the necessary. Overall, fibrosarcoma of bone is the main conditions; it occurred in the bone marrow or bone outer membrane, except for the soft tissue to be intrusive or violations of fibrosarcoma of bone tissue. Its main constituents and the general soft tissue fibrosarcoma exactly the same. Clinical manifestations】 【age of onset of relatively uniform distribution, not as good osteosarcoma with special age, but under 10 years of age, 50 years of age and above, less morbidity. An equal ratio of men and women. Tumor growth slower, and the pain does not show, very little systemic symptoms, serum alkaline phosphatase unchanged. Attending ordinary patients, have considerable shadow of the soft tissue tumors. Bone damage often confined to the side of the transparent defect was irregular. When tumor invasion marrow, bone destruction relatively extensive and widespread, a single cyst-like, but uneven edge cyst, without expansion of the phenomenon. This 2:00 and bone cyst different. To confirm the diagnosis, biopsy should be made. [Treatment and prognosis] tumors occurred in the location easy to cut governance, the concept itself tumor earlier, the bone destruction relatively limited, may consider the limitations of relatively complete tumor resection, if necessary, can make up for the bone defect implant Unit after attention to the long-term review. If the tumor recurrence, should be employed amputation, concurrent chemotherapy. Any invasion of a wide range of tumors, regardless of their degree of malignancy how, and shall be used for the treatment of osteosarcoma of the same methods. Lung metastases found in more. Primary fibrosarcoma poor prognosis, the five-year cure rate with osteosarcoma or similar chondrosarcoma. Secondary fibrosarcoma better prognosis, and of similar secondary cartilage.
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