Thursday, March 6, 2008

Primary vasculitis which clinical performance?

Such diseases occur in middle-aged and older men, the highest age group of 50-60-year-old, male, female ratio was 13:1. Patchy in winter. (1) extra - renal manifestations : irregular fever, skin rash, joint pain, muscle pain, weight loss, Mr neuritis, abdominal pain and gastrointestinal symptoms. Pulmonary inter alia kidney involvement of the most vulnerable organs. Pulmonary hemorrhage about vasculitis patients 30% ~ 50%. Pulmonary and renal involvement extent consistent. The clinical manifestations of allergic asthma, sputum or hemoptysis, X-ray showed signs of pulmonary hemorrhage, patients can have serious breathing difficulties. even respiratory failure, and some patients may die of hemoptysis. Chest radiography in the diagnosis of a certain significance, microscopic polyarteritis nodosa-more than double the performance of the middle and lower lung lobular inflammation, Wegener granulomatosis patients can be seen 90% of non-specific inflammatory infiltration, have a leaf or leaf compact round or oval shadow, the center often empty or showing the nature, but also to miliary lesions. In addition, sinusitis can be found in 25% ~ 30% of patients. (2) performance of renal involvement : About 1 / 3 haematuria, was under the microscope deformation of the red blood cells and red blood cell type, proteinuria, But rare nephrotic syndrome, hypertension is rare, there was also a serious and even radical nature hypertension. Most sexual oliguric patients, renal dysfunction, half the patients were rapidly progressive glomerulonephritis process. a few patients were slowly progressive renal failure, and another individual patients with normal renal function.

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