Thermal treatment of leukemia

Normal hematopoietic stem cells in the environment of 43 ° C, despite the normal survival or growth of leukemia cells in more than 41.5 ° C, which began to die. Microwave radiation is highly selective to kill leukemia cells, bone marrow used in microwave purification, a 4.9% reduction in relapse rate. The high temperature treatment mechanism : (1) of tumor cells than normal cells sensitive; (2) to radiotherapy or chemotherapy is not sensitive tumor cells "S" period, but sensitive to heat; (3) radiotherapy or chemotherapy sensitive to the bone marrow of the hypoxic cells are sensitive to heat; (4) high-temperature can prevent tumor cells sublethal injury and fatal damage and repair; (5) the photosensitizer enhanced cytotoxicity. These medications and treatment while applications will greatly increase the kill leukemia cells. Know, as long as patients with a residual leukemia cells, and natural proliferation of 160 days leukemia can increase the number of clinical relapses. The above method of treatment, the body is very difficult for the leukemia cells thorough kill. Laser photosensitizer activated Act Mitsuno small, weak penetration, it is difficult even to a role in each tumor cells, and impossible role in the deep tumor cells, it may be superficial tumor cells and normal cells, has reached lethal dose, but the deep tumor cells, no effect of thermal radiation . If the United States than the photosensitive material intake is double that of the anti - leukemia strong intensity 3.2 times faster kill, the side effects of low-LF-019 photosensitizer and a small amount of chemotherapy drugs, suction to join the bone marrow in vitro blood within 48 to 72 hours metabolism, reuse WL special type of bone marrow purification machine, to ultraviolet A, B, C-wave mixing, 41.5 ~ 43 ° C temperature, bone marrow blood circulation, mobility, exposure to direct heat treatment and minimal dose chemotherapy, rendering a cell uniform acceptance 5 ~ 10 biological dose the refractory - 30 ~ 50% leukemia cells (immature cells) in bone marrow blood, by the above, the purification of blood before and after the bone marrow, stem cell colony culture and PCR detection, decontamination before vigorous growth of leukemia cells, while the normal hematopoietic stem cell growth, after purification, only the normal hematopoietic stem cell growth, and no leukemia cells. Hunan College of Traditional Chinese Medicine Hospital Hematology first application of the bone marrow purification method of refractory or relapsed acute leukemia for autologous bone marrow transplantation, will enable patients reached complete remission, and healthy long-term survival.