What is Cirrhosis refractory ascites?

Cirrhosis refractory ascites (KA) is a pulp stood larger, continuing for more than three months. Conventional methods of diuretic response to the loss of water and sodium were not tolerance, serum sodium "1300mmol / L, natriuretic "10mmol / L, urinary sodium / potassium urine" a free water clearance rate "1. glomerular filtration rate and renal plasma flow in both lower. Such patients with ascites significantly reduce the circulatory function, despite the splanchnic vascular bed significant hematoma, but cardiac output, effective renal blood flow in both blood volume reduction if they continue to use such strong diuretic furosemide, the diuretic effect not only poor, and often blood renal plasma flow and glomerular filtration rate risk could lead to hepatorenal syndrome, severe electrolyte imbalance, life-threatening.