How diagnosis, differential diagnosis uric acid nephropathy?

Middle-aged and older men kidney patients with joint disease and urinary stone disease, and should be suspected of the disease. Acidic urine, serum uric acid increased urinary uric acid stone elements can be diagnosed. Of the disease and kidney disease should be secondary hyperuricemia as well. Identification as follows : ① uric acid nephropathy increased serum uric acid than urea nitrogen and creatinine were remarkable, but uric acid / creatinine "2.5. ② gouty arthritis obvious nephropathy, primary glomerular diseases even hyperuricemia rarely occurred arthritis. ③ long history of uric acid nephropathy, usually first tubular dysfunction and renal impairment mild renal dysfunction progress has been slow. Renal biopsy to see birefrigence uric acid crystals may establish uric acid nephropathy diagnosis. 