Thursday, March 6, 2008
Lupus nephritis which kidney damage performance?
Systemic lupus kidney damage symptoms including glomerular, tubulointerstitial, and renal vascular disease in a series of symptoms, onset can also be hidden sharp attack, the course is long, with or without symptoms, kidney damage can be the only clinical manifestations. Edema is a common clinical manifestations, are often the main reason for attending patients. Nocturia increase is one of the early symptoms often reflect the urinary concentration dysfunction. About 1 / 6 of the patients at the time of diagnosis of renal function have varying degrees of decline. According to its clinical manifestations, can be divided into the following types : (a) or asymptomatic proteinuria (and) Hematuria : The more common type, no edema, hypertension, mainly mild to moderate proteinuria ( "2.5 g / d) or (and) hematuria. (2) acute nephritis syndrome : a rare, clinically resembles streptococcal infection after acute nephritis, acute onset, hematuria, proteinuria, urinary tube can have edema, hypertension and even acute renal failure can occur. (3) rapidly progressive glomerulonephritis type syndrome : a rare, clinically resembles rapidly progressive glomerulonephritis, a sharp onset and rapid development there anuria or oliguria, hematuria, proteinuria, urinary tube can be swelling, often without hypertension or mild hypertension. rapidly and the development of anemia and hypoproteinemia, renal function deteriorated rapidly in the weeks and months inside uremia. (4) nephrotic syndrome : common type, about 60% of patients with renal damage performance of this type. Clinical manifestations of massive proteinuria (3.5g / d) and hypoproteinemia may have serious edema, but not necessarily to hypercholesterolemia. If not treated in time, the most in two-three years to develop uremia. This is easy with idiopathic nephrotic syndrome confused, it should be noted. (5) chronic nephritis syndrome : performance for sustained proteinuria, hematuria, and urinary tube varying degrees of edema, hypertension, anemia and renal insufficiency. Course of a long and protracted holdback, and the prognosis is poor. (6) tubular-type syndrome : a rare performance of renal tubular acidosis, increased nocturia, edema, hypertension, Urine β2 - microglobulin increased, and half of patients with renal dysfunction. (7) clinical "quiet" type : clinical symptoms and no signs of kidney involvement performance of conventional urine tests negative But pathological examination (particularly electron microscopy and immunofluorescence) positive.
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