Thursday, March 6, 2008
Systemic lupus erythematosus diagnostic criteria?
The disease most of the diagnostic criteria for setting up a reference to the United States Institute of the 1982 classification criteria : (a) the Department of malar erythema : across the zygomatic flat or higher than the fixed skin erythema, often without implicating the nasolabial site; (2) discoid lupus : Uplift erythema overlying a horny sexual subtype and hair follicle embolization, old lesions can scar the skin atrophy; (3) Light Allergy : Solar irradiation caused skin allergies; (4) oral ulcers : Oral or nasopharyngeal painless ulcer; (5) arthritis : non-erosive arthritis involving two or more around the joints, the joints characterized by pain or exudate; (6) Serositis : ① pleurisy -- chest pain, pleural friction sound or pleural effusion. ② pericarditis -- abnormal electrocardiogram, Pericardial friction sound or pericardial effusion. (7) renal lesions : ① proteinuria "0.5g / d or >+++; ② cell tube -- for RBC, hemoglobin, or particles of mixed-tube type; (8) the nervous system anomalies : ① convulsion -- not drugs or metabolic disorders, such as uremia, ketoacidosis or electrolyte imbalance caused; ② mental illness -- non-drug or metabolic disorders, such as uremia, ketoacidosis or electrolyte imbalance caused; (9) hematologic abnormalities : hemolytic anemia with reticulocyte increased; or leukopenia "4 × 109 / L, at least two times; lymphocytes or reduce "15 × 109 / L, at least two times; Thrombocytopenia "100 × 109 / L (except for the influence of drugs); (10) immunologic abnormalities : LE-positive cells, or anti-dsDNA antibody positive, or positive anti - Sm antibodies, or syphilis serology test false positive; (11) anti-nuclear antibodies : anti-nuclear immunofluorescence antibody titer anomaly or the equivalent of the Act other abnormal test titer, ruled out the drug-induced "lupus syndrome." Meet the above four or four and above can diagnosis of this disease.
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