Primary vasculitis in the diagnosis and differential diagnos

As such the clinical performance of the lack of specificity, more variability, the clinical diagnosis more difficult. For, nephritic syndrome in the elderly, especially general accompanied by systemic symptoms, progressive renal failure and / or pulmonary hemorrhage should consider the possibility of this disease. Renal histological examination showed segmental necrotizing crescentic glomerulonephritis associated with the formation, and immunopathological examination no or only trace immunoglobulin deposition who help diagnosis. Other parts of the biopsy will not be easily vasculitis evidence. Reports can help muscle biopsy diagnosis, has proved arteriography no diagnosis. The general lack of laboratory diagnostic specificity. Patients can be quickly ESR and C-reactive protein positive, γ - globulin increases, the C3 more normal. WBC was mostly higher, there are more cell anemia is pigment. The most valuable of serum anti-neutrophil cytoplasmic antibody (ANCA Determination of serum) Even in the absence of pathological basis ANCA also help the diagnosis. ANCA positive but also occasionally in the secondary vasculitis, systemic lupus erythematosus, Henoch - Schonlein purpura. cryoglobulinemia, should pay attention to differential. 