With chronic lymphatic leukemia performance

Typical B-cell slow leaching onset slow, early often asymptomatic, can be physical or occasional blood routine examination found, or some other hepatosplenomegaly due to lymph node was found.
(1) The most common lymphadenopathy (70%), for the systemic, mild to moderate swelling, dual significantly enlarged, no tenderness, inconsistent with rubber flu, and skin adhesive is not common in neck Department, armpits and groin and other places. Tonsil, lacrimal glands, salivary glands tired timely, can produce Mikulicz syndrome.
(B) hepatosplenomegaly splenomegaly common (40%), mild to moderate swelling, pelvic up late, even splenic infarction may occur or splenic rupture. Hepatomegaly (10%) than the degree of spleen, when obviously swollen with impaired liver function, often suggested that advanced cases.
(C) Other invasion performance 50% patients have skin manifestations, slower tablets common, specificity, such as nodules, Erythroderma diseases, but also non-specific such as itching etc.. Infiltration of the stomach and small intestine common satisfied by that, abdominal distension, dyspepsia, and soiled, such as diarrhea. Main pulmonary infiltration diffuse nodular, Miliary infiltration (40%), and pleural effusion (15%). Often bloody pleural effusion, lymphatic obstruction may also occur due to chylothorax. A common bone disease and bone decalcification sparse (5%), osteolytic rare. Pathological examination more than 60 percent of patients with kidney bilateral leukemia infiltration, but generally minor lesions, about 20% of the patients with microscopic hematuria and proteinuria. Dot nervous system lesions with a brain infiltration, even of brain tumor nodule formation, but also in meninges, seven pairs of cranial nerves, hypothalamus, pituitary and peripheral neuropathy, intracranial pressure can be increased.
(D) immunodeficiency performance or herpes simplex zoster incidence higher. Patients easily have purulent infection such as pneumonia. Also associated with a second cancer, particularly colon and skin cancer. At the same time associated with diffuse cell lymphoma, known as Richter syndrome, a rate of about 3.3 percent. In addition can be associated with rheumatoid arthritis and myasthenia gravis, and so on.
T cells slow leaching characteristics of the clinical onset is rapid, hepatosplenomegaly, lymphocytes moderate increase, and often violations of the central nervous system, gonadal and deep dermis, the poor response to treatment, the survival time is short.